Enzymatic assay of urinary formic acid as an index of methanol exposure.

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An enzymatic method for the determination of formic acid.

* Present address, Department of Biochemistry, University of California, Berkeley 4, California. 1 The following abbreviations have been used; THF, tetrahydrofolic acid; lo-formyl-THF, N*o-formyltetrahydrofolic acid; 5,10-methenyl-THF, the cyclic N6-NrOimidazolinium derivative of 5-formyl-THF (anhydroleucovorin or anhydrocitrovorum factor) ; ATP, adenosine triphosphate; ADP, adenosine diphospha...

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Synthesis of Naphthopyranopyrimidines Using Formic Acid as an Effective Catalyst under Solvent-free Conditions

An environmentally friendly, one-pot, three-component synthesis of 8,10-dimethyl-12-aryl-12H-naphtho[1′,2′:5,6]pyrano[2,3-d]pyrimidine-9,11-diones was achieved via coupling aromatic of aldehydes, β-naphthol and 6-amino-1,3-dimethyl uracil in the presence of formic acid as a catalyst under solvent-free conditions at 90 °C. This method has several advantages, such as efficiency, good yield, short...

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Effects of methanol and formic acid on human platelet aggregation

BACKGROUND Although ethanol is known to inhibit platelet aggregation, the effects of another variant of alcohol, methanol, have not been reported. The purpose of this study was to determine whether methanol and its metabolite, formic acid, affect Ca2+ entry into and subsequent aggregation of platelets in vitro. METHODS Ca2+ entry into and aggregation of human platelets were measured by spectr...

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ژورنال

عنوان ژورنال: INDUSTRIAL HEALTH

سال: 1989

ISSN: 0019-8366,1880-8026

DOI: 10.2486/indhealth.27.125